Complement-Fixation Technique: III. THE WASSERMANN REACTION

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Complement-Fixation Technique: II. THE TITRATION OF WASSERMANN ANTIGEN.

After material has been produced for use as an antigen in a complement fixation test it is necessary to find out if the finished product has any complement-fixing ability in the presence of a serum containing a suitable antibody. Moreover, the proposed antigen must not have any undue anticomplementary property, and the " gap" between its anticomplementary titre and its complement fixing titre m...

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An examination of the treponemal Wassermann reaction and Reiter protein complement-fixation test.

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An Examination of the Treponemal Wassermann Reaction and Reiter Protein Complement-fixation

Less than one year after the description of the Treponema pallidum by Schaudinn and Hoffman, the first report of the application of the complementfixation reaction of Bordet and Gengou (1901) to the diagnosis of human syphilis was published in Budapest by Detre (1906), exactly 2 weeks after the appearance of the classical paper "A Sero-diagnostic Reaction in Syphilis" by Wassermann, Neisser, an...

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The Gomez Complement-fixation Reaction

Much has been done, but there is still much to be accomplished in the matter of tests for infection and immunity in leprosy. To be of help to the clinicians it is not sufficient for a test to be positive among the inmates of a leper asylum; it is necessary that it should work also in free surroundings where are met the doubtful cases, toward the' detection of which the greatest vigilance should...

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Concerning the Wassermann Reaction

tionally collected and kept for some time, is a very poor control. Some positive sera give a complete fixation of the usual one or more MHD of the complement in a 1 in 200 dilution; others can do so in 1 in 5 dilution only. The margin.of variation allowed for in this control, 5 to 200, is too wide to be useful in indicating whether the antigen-antibody systems involved in the reaction of comple...

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ژورنال

عنوان ژورنال: Sexually Transmitted Infections

سال: 1950

ISSN: 1368-4973

DOI: 10.1136/sti.26.4.172